Fig. 1

CLCA2 mRNA and protein expression levels in NPC tissues and cell lines. a Levels of CLCA2 protein expression in NPC tissues are shown under both low and high magnifications of a light microscope, depressed CLCA2 level correlates with shorter overall survival and distants metastasis-free survival in NPC patients. Scale bars, 200 μm and 50 μm. b. The overall survival (OS) rate was significantly higher in the higher CLCA2 group. c. The distants metastasis-free survival (DMFS) rate was also significantly higher in the high-CLCA2 group. d-e CLCA2 was differentially expressed in NPC cell in mRNA and protein levels. f Real-time quantitative PCR analysis of CLCA2 mRNA expression levels in NPC (n = 34) and normal nasopharyngeal epithelial tissues (n = 28),The mRNA levels of CLCA2 in nasopharyngeal carcinoma (NPC) tissues were lower than the noncancerous nasopharyngeal tissues (NP), P value, result of unpaired t test