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Fig. 5 | Journal of Experimental & Clinical Cancer Research

Fig. 5

From: Along with its favorable prognostic role, CLCA2 inhibits growth and metastasis of nasopharyngeal carcinoma cells via inhibition of FAK/ERK signaling

Fig. 5

CLCA2 inhibits NPC cellular migration and invasion through suppressing FAK/ERK pathway. a Western blotting analysis of P-FAK(397), P-FAK(975), FAK, P-ERK, ERK(1/2) expression levels after overexpression of CLCA2 and silencing of CLCA2. b-c The expression the FAK/ERK signaling in CLCA2 silencing S26 and SUNE-1 cells after PF-573228 or U0126 treatment was detected by immunoblotting. After treatment with 1 μM PF-573228, 2 μM U0126 or DMSO for 8 h, cell lysates were harvested for western blot detection. Relative gradation corrected by GAPDH is shown below each band

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