Fig. 3
From: CDK5RAP3 suppresses Wnt/β-catenin signaling by inhibiting AKT phosphorylation in gastric cancer
AKT silencing repressed the migration and invasion of CDK5RAP3 knockdown gastric cancer cells. a-b The stimulatory effect of CDK5RAP3 downregulation on AGS and HGC-27 cell migration and invasion was rescued by AKT siRNA transfection. The data are presented as the mean ± SD (**, P < 0.01; ***, P < 0.001; ns, no significance). c When AKT was knocked down, the protein levels of E-cadherin, N-cadherin and Vimentin were not significantly changed whether CDK5RAP3 was knocked down or overexpressed (**, P < 0.01; ***, P < 0.001; ns, no significance)