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Table 1 Description of the study population between colorectal cancer patients with osteoglycin low and high expression

From: Osteoglycin (OGN) reverses epithelial to mesenchymal transition and invasiveness in colorectal cancer via EGFR/Akt pathway

Variables, N (%)

OGN

P value

Low(N = 163)

High(N = 109)

Gender

   

 Male

101(62)

62(56.9)

0.40

 Female

62(38)

47(43.1)

 

Age, years

56.9 ± 10.7

57.3 ± 11.6

0.79

TNM stage

  

0.43

 I

14(8.6)

7(6.4)

 

 II

49(30.1)

32(29.4)

 

 III

73(44.8)

58(53.2)

 

 IV

27(16.6)

12(11.0)

 

N stage

  

0.16

 N0

74(45.4)

46(42.2)

 

 N1

53(32.5)

28(25.7)

 

 N2

36(22.1)

35(32.1)

 

M stage

  

0.43

 M0

136(83.4)

97(89.0)

 

 M1

27(16.6)

12(11.0)

 

Grade

  

0.55

 Well/ moderate

118(72.4)

85(78.0)

 

 poor

34(20.9)

19(17.4)

 

T stage

  

0.74

 T2

27(16.6)

16(14.7)

 

 T3

30(18.4)

24(22.0)

 

 T4

106(65.0)

69(63.3)

 

Histological type

  

0.28

 Adenocarcinoma

152(93.3)

105(96.3)

 

 Mucinous

11(6.7)

4(3.7)

 

Lymph node examined

  

0.17

 Median

15 ± 7

16 ± 6

 

Perineural invasion

  

0.26

 Negative

133(82.1)

95(87.2)

 

 Positive

29(17.9)

14(12.8)

 

Vascular invasion

  

0.25

 Negative

108(66.3)

75(68.8)

 

 Positive

51(31.3)

34(31.2)

 

Adjuvant Chemotherapy

  

0.37

 No

30(18.4)

18(16.5)

 

 Yes

108(66.3)

80(73.4)

 

MS status/MMR status

  

0.06

 MSS/MMR-proficient

111(68.1)

62(56.9)

 

 MSI/MMR-deficient

52(31.9)

47(43.1)

 
  1. MMR indicates mismatch repair, MS microsatellite, MSS microsatellite stability, MSI microsatellite instability