Fig. 7
From: miR-148b-3p inhibits gastric cancer metastasis by inhibiting the Dock6/Rac1/Cdc42 axis
miR-148b-3p promotes the motility of GC cells by activating Rac1 and Cdc42. a GST pull-down and western blot analysis of the expression levels of GTP-Rac1 and GTP-Cdc42 in the indicated GC cells. b A miR-148b-3p inhibitor increased the migration and invasion abilities of SGC-7901NM cells, while a Rac1 inhibitor (NSC23766) and Cdc42 inhibitor (ML141) blocked the miR-148b-3p inhibitor-mediated GC cell migration and invasion as detected by transwell studies. Scale bars, 50 μm. **P < 0.01, ***P < 0.001