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Fig. 3 | Journal of Experimental & Clinical Cancer Research

Fig. 3

From: The dysregulation of tRNAs and tRNA derivatives in cancer

Fig. 3

tRNA derivatives exerted their effects through different pathways. a tRNA derivatives promoted cell proliferation and the progression of G0/G1 cell cycle by regulating the expression of AURKA. b Both tRNA derivatives and endogenous oncogene transcripts competed with YBX1, suppressing the progression of cancer and preventing the translation of eIF4G/A. c tRNA derivatives promoted the translation of ribosomal protein mRNAs, subsequently enhancing cell proliferation and viability

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