Fig. 6

The expression of TRAF6 was elevated in OSCC patients. a The protein level of TRAF6 in OSCC samples and paired normal tissues was analyzed by Western blot. b The protein level of TRAF6 in human OSCC samples and paired normal tissues was analyzed by IHC. Cancer-specific survival by the Kaplan-Meier method by (c) the expression of TRAF6 in all patients (p = 0.280), (d) the expression of TRAF6 in patients with well differentiated tumors (N = 60; p = 0.074), (e) AJCC N stage (N0–1 vs. N2–3) (p = 0.034), and (f) Risk groups stratified by differentiation and expression of TRAF6 (p = 0.033)