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Table 5 Multivariate analysis with respect to DFS and OS in invasive breast cancer

From: NHERF1 and tumor microenvironment: a new scene in invasive breast carcinoma

 

categorical

continuous

Characteristics

HR (95% CI)a

p-value a

HR (95% CI)a

p-value a

cNHERF1

0.63 (0.25, 1.60)

0.337

0.99 (0.96, 1.02)

0.416

nNHERF1

0.60 (0.07, 5.167)

0.640

0.89 (0.70, 1.12)

0.319

mNHERF1

3.71 (0.98, 13.99)

0.053

1.09 (1.02, 1.17)

0.011

cVEGF

0.63 (0.25, 1.61)

0.333

0.99 (0.97, 1.01)

0.249

cVEGFR1

0.64 (0.28, 1.48)

0.297

1.00 (0.98, 1.02)

0.826

MVD

0.54 (0.23, 1.29)

0.165

0.97 (0.91, 1.04)

0.442

nHIF-1α

0.69 (0.24, 2.02)

0.504

0.99 (0.95, 1.03)

0.520

nTWIST1

0.14 (0.05, 0.43)

0.001

0.92 (0.87, 0.97)

0.003

  1. ahazard-ratio (HR) and p-value for DFS computed using the multivariate Cox proportional hazard regression model with categorical and continuous variables; HR for OS cannot be computed due to the low number of events