Fig. 5

KIAA1199 overexpression reversed the inhibition effect of miR-600 mimic on migration and invasion of CRC cells. SW620 and LOVO cells were transfected with NC, miR-600 mimic, miR-600 mimic+pcDNA, miR-600 mimic+pcDNA-KIAA1199. a Transwell assay showed that KIAA1199 overexpression reversed the inhibition effect of miR-600 mimic on migration of CRC cells. b Transwell assay showed that KIAA1199 overexpression reversed the inhibition effect of miR-600 mimic on invasion of CRC cells. c Western blot analysis showed that KIAA1199 overexpression reversed the inhibition effect of miR-600 mimic on the expression of N-cadherin, vimentin and Fibronectin, and the promotion effect of miR-600 mimic on the expression of E-cadherin