Fig. 10
From: The oncogenic neurotrophin receptor tropomyosin-related kinase variant, TrkAIII
Potential TrkAIII-targeted and alternative therapeutic approaches to TrkAIII expressing cancers. Representation of TrkAIII behaviour, oncogenic mechanisms and potential therapeutic inhibitors of TrkAIII activity, expression and down stream signaling, which either alone or in combination with genotoxic-, oxidative and/or ER stress-inducing cancer drugs may be of therapeutic benefit in TrkAIII expressing cancers