Fig. 2
From: The oncogenic neurotrophin receptor tropomyosin-related kinase variant, TrkAIII
TrkAIII is expressed in primary and secondary to metastatic melanomas. a) Representative RT-PCR agarose gel, demonstrating exclusive TrkAIII expression in a single primary melanoma (Pri Mel) and single melanoma metastasis (Mel Met) samples compared to predominant fully spliced TrkA expression in IMR32 NB cells and lack of TrkA expression in a sample of normal human skin plus TrkAIII and TrkA cDNA RT-PCR product controls and GAPDH, as a loading control. b) Representative TrkAIII exon 5/8 splice junction sequence from a melanoma metastasis