Fig. 1

miR-9 was reduced in exosomes derived from cultured NPC cells and plasma samples. a Representative images of transmission electron microscopy for exosome derived from NP69, 5-8F and CNE1 cells. Scale bars, 50 nm. b CD63 and TSG101 (common exosomal markers) immunoblots of exosomes derived from above three cell lines. c The expression of miR-9 in the exosomes derived from NP69, 5-8F and CNE1 cells. d Examination of exosomal miR-9 level in plasma samples of NPC patients (n = 110) and healthy controls (n = 60). e A high level of plasma exosomal miR-9 predicted good survival of NPC patients. **, P < 0.01