Fig. 6

Quantitative proteomics analysis for exosomes extracted from CM of SCC25 and Cal27 cells. a. Venn diagram indicating 891 proteins shared between SCC25- and Cal27- exosomes. b. Proteins shared in SCC25- and Cal27- exosomes were filed based on KEGG pathway analysis by focusing on inflammatory related pathways, PI3K-Akt, HIF-1, MAPK, Notch, NF-κB, and Ras signaling pathways. Proteins with < 5% coverage were excluded. c. Among the filtered 39 proteins, functions were analyzed through UniProtKB. THBS1 was chosen for further analysis