Fig. 2

SIRT7 impairs OSCC cells migration and invasion in vitro. (a) The results of western blot analysis and its quantitative analysis showed successful upregulation and downregulation of SIRT7 levels in HSC3 cells using lentiviral particles. (b) The results of western blot analysis and its quantitative analysis showed successful upregulation and downregulation of SIRT7 levels in OECM1 cells using lentiviral particles. (c) The results of wound migration assay and quantitative analysis of the effect SIRT7 on HSC3 cells migration. (d) The results of wound migration assay and quantitative analysis of the effect SIRT7 on OECM1 cells migration. (e) The results of transwell invasion assay and quantitative analysis of the effect SIRT7 on HSC3 and OECM1 cells invasion. N: normal control; OE: overexpression; Sh: shRNA that used for SIRT7 knockdown; NC: negative control. * P < 0.05 when compared with group N