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Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: Circular RNA IARS (circ-IARS) secreted by pancreatic cancer cells and located within exosomes regulates endothelial monolayer permeability to promote tumor metastasis

Fig. 2

circ-IARS, highly expressed in pancreatic cancer, is an independent risk factor for PDAC patient survival. a qRT-PCR validation of the relative expression levels of circ-IARS in Hs 766 T and Hs 766 T-L2 cells. b Relative expression levels of circ-IARS and linear-IARS in 25 pairs of pancreatic tumor tissue and adjacent normal tissue. c Expression levels of circ-IARS in plasma exosomes from 20 pairs of PDAC patients with or without metastasis were assessed by qRT-PCR. d K-M survival curves for survival of all 79 patients with PDAC according to the relative expression levels of circ-IARS in tumor tissues

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