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Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: Yes-associated protein (YAP) binds to HIF-1α and sustains HIF-1α protein stability to promote hepatocellular carcinoma cell glycolysis under hypoxic stress

Fig. 2

YAP correlated strongly with HIF-1α. a GSEA indicated a significantly enhanced expression of Hippo signaling genes in HCC tissues from the TCGA database. b The expression of YAP mRNA is positively correlated with the expression of HIF-1α mRNA in 369 cases of HCC tissues from TCGA, which were analysed by GEPIA. c Real-time PCR showed YAP mRNA correlated strongly with HIF-1α mRNA in 54 pairs of HCC tissues. d Western blot showed the representative expression of YAP and HIF-1α in HCC tissues and adjacent tissues

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