Table 1 Plating efficiency (PE) and surviving fraction (SF) values in AsPC-1, Capan-2 and BxPC-3
AsPC-1 | Capan-2 | BxPC-3 | ||||
|---|---|---|---|---|---|---|
PE % | SF % | PE % | SF % | PE % | SF % | |
Control | 42.88 | 100.00 | 50.07 | 100.00 | 30.63 | 100.00 |
24 μM Erlo | 34.28 | 79.94 | 43.50 | 86.88 | 19.37 | 63.22 |
Low concentrations of Nelfinavir and Nitroxoline | ||||||
12 μM Nelfi | 14.00 | 32.65 | 20.97 | 41.88 | 11.43 | 37.32 |
10 μM Nitro | 0.00 | 0.00 | 0.73 | 1.46 | 2.70 | 8.81 |
12 μM Nelfi + 10 μM Nitro | 0.00 | 0.00 | 0.83 | 1.66 | 4.50 | 14.69 |
24 μM Erlo + 12 μM Nelfi + 10 μM Nitro | 0.00 | 0.00 | 0.80 | 1.60 | 2.00 | 6.53 |
High concentrations of Nelfinavir and Nitroxoline | ||||||
25 μM Nelfi | 0.00 | 0.00 | 1.20 | 2.40 | 0.23 | 0.76 |
40 μM Nitro | 0.00 | 0.00 | 0.57 | 1.13 | 0.20 | 0.65 |
25 μM Nelfi + 40 μM Nitro | 0.00 | 0.00 | 0.47 | 0.93 | 0.20 | 0.65 |
24 μM Erlo + 25 μM Nelfi + 40 μM Nitro | 0.00 | 0.00 | 0.23 | 0.47 | 0.17 | 0.54 |