Fig. 1
From: Inhibition of STAT3 blocks protein synthesis and tumor metastasis in osteosarcoma cells
NP decreases cell viability and proliferation of human osteosarcoma cells. a, Human osteosarcoma cells (143B, MG63, U2OS, KHOS) were treated with vehicle (Veh) (0.1% DMSO) or NP at various concentrations for 24, 48, and 72 h, and cell viability was measured by MTS assay as described in the Methods section of the text. b and c, The cell colony formation assay was carried out in 143B and MG63 treated with Veh or NP at indicated concentrations. d, 143B cells were treated with Veh or NP for 24 h and analyzed by immunofluorescence using anti–Ki-67 antibodies. The data are representative of 3 independent experiments. *P < 0.05 versus vehicle control; ** P < 0.01 versus vehicle control