Table 1 Relationship between ATF3 protein expression and clinicopathological features in HCC patients
Clinicopathological Features | Number of cases | ATF3 expression | P Value | |
|---|---|---|---|---|
Low N (%) | High N (%) | |||
Age (years) | ||||
  ≤ 50 | 159 | 27 (64.30) | 132 (68.40) | 0.606 |
  > 50 | 76 | 15 (35.70) | 61 (31.60) |  |
Gender | ||||
 Male | 190 | 34 (81.00) | 156 (80.40) | 0.936 |
 Female | 46 | 8 (19.00) | 38 (19.60) |  |
Tumor size | ||||
  ≤ 5 cm | 113 | 19 (47.50) | 94 (49.70) | 0.797 |
  > 5 cm | 116 | 21 (52.50) | 95 (50.30) |  |
AFP (ng/ml) | ||||
  ≤ 20 | 79 | 12 (28.60) | 67 (35.30) | 0.408 |
  > 20 | 153 | 30 (71.40) | 123 (64.70) |  |
HBV infection | ||||
 Negative | 42 | 9 (22.50) | 33 (17.50) | 0.454 |
 Positive | 187 | 31 (77.50) | 156 (82.50) |  |
Cirrhosis | ||||
 Absent | 38 | 10 (23.80) | 28 (14.40) | 0.134 |
 Present | 137 | 32 (76.20) | 166 (85.60) |  |
Intrahepatic metastasis | ||||
 Absent | 161 | 23 (54.80) | 138 (71.10) | 0.039* |
 Present | 75 | 19 (45.20) | 56 (28.90) |  |
Histological grade | ||||
 I, II |  | 19 (45.2) | 100 (51.5) | 0.458 |
 III, IV |  | 23 (54.8) | 94 (48.5) |  |