Fig. 9

The molecular mechanism underlying that microRNA-31-5p regulates chemosensitivity by preventing the nuclear location of PARP1 in hepatocellular carcinoma. miR-31-5p modulated chemosensitivity by altering the intracellular distribution of OXA in HCC. miR-31-5p prevents the nuclear localization of PARP1 through protein-protein interaction with ABCB9 to regulate OXA-based chemosensitivity