Fig. 1

Lentinan (LNT) exhibits better antitumor effects at a relatively lower dose compared with a higher dose. a Experimental design: FVB mice were subcutaneously (s.c.) inoculated with 2 × 10⁵ LAP0297 lung cancer cells on the right flank. When tumors reached 4 × 4 mm in diameter, mice were randomly divided into 6 groups and received i.p. injection of different doses of LNT (0.25 mg/kg, 0.5 mg/kg, 1.0 mg/kg, 2.0 mg/kg, and 5.0 mg/kg) daily for 10 days. b LAP0297 lung tumor-bearing mice received different doses of LNT treatments. c Tumor weight was measured at the end of the treatments. NS: control group treated with saline. All data in this report are presented as means ± SEM. * p < 0.05, ** p < 0,01, *** p < 0.001