Fig. 5

XIST modulates miR-34a downstream MET-PI3K-AKT signaling via miR-34a (a-c) KAT18 and FTC113 cells were co-transfected with si-XIST and miR-34a inhibitor; the protein levels of MET, p-PI3K, PI3K, p-AKT and AKT were examined using Immunoblotting assays. The data are presented as mean ± SD of three independent experiments. **P < 0.01, compared to control group; ##P < 0.01, compared to si-XIST group