Table 1 Correlation between TSPAN1 staining and clinicopathologic characteristics in 60 CCA patients
Variables | TSPAN1 staining | ||
|---|---|---|---|
Positive(n = 42) | Negative/low(n = 18) | P value | |
n(%) | n(%) | ||
Age (years) | |||
> 60 | 27(64.29%) | 11(61.11%) | 0.8151 |
≤ 60 | 15(35.71%) | 7(38.89%) | |
Gender | |||
Male | 23(54.76%) | 9(50.00%) | 0.7347 |
Female | 19(45.24%) | 9(50.00%) | |
Histological differentiation | |||
Well | 10(23.81%) | 8(44.44%) | 0.2752 |
Moderate | 15(35.71%) | 5(27.78%) | |
Poor | 17(40.48%) | 5(27.78%) | |
TNM stage | |||
I-II | 16(38.10%) | 14(77.78%) | 0.0048 |
III-IV | 26(61.90%) | 4(22.22%) | |
CA19–9 (U/ml) | |||
≤ 37 | 13(30.95%) | 5(27.78%) | 0.8058 |
> 37 | 29(69.05%) | 13(72.22%) | |
Lymph node metastasis | |||
No | 19(45.24%) | 14(77.78%) | 0.0202 |
Yes | 23(54.76%) | 4(22.22%) | |
Distant metastasis | |||
No | 29(69.05%) | 17(94.44%) | 0.0331 |
Yes | 13(30.95%) | 1(5.56%) | |