Table 2 Cytokines Levels in human melanoma cell lines by Luminex analysis
From: TNF-alpha and metalloproteases as key players in melanoma cells aggressiveness
Cytokines | SK-MEL-28 (pg/ml/mgProt) | A375 (pg/ml/mgProt) | p-Value | A375 vs SK-MEL-28 |
|---|---|---|---|---|
PDGF-bb | 5.79 ± 2.5 | 0.00 ± 0.00 | 0.0491 | down-regulated |
IL-1β | 5.69 ± 3.59 | 1.98 ± 1.06 | 0.0001 | down-regulated |
IL-9 | 7228.00 ± 1003.00 | 1310.91 ± 446.08 | 0.0121 | down-regulated |
IP-10 | 83.44 ± 16.52 | 2.56 ± 07 | 0.0011 | down-regulated |
IL-8 | 322.20 ± 136.72 | 64.34 ± 13.87 | 0.0314 | down-regulated |
IL-1ra | 80.35 ± 4.19 | 33.93 ± 16.17 | 0.0086 | down-regulated |
G-CSF | 81.68 ± 14.20 | 22.94 ± 19.73 | 0.0138 | down-regulated |
IL-6 | 1.06 ± 0.04 | 5.86 ± 2.33 | 0.0235 | up-regulated |
IL-12 | 4.53 ± 2.59 | 16.38 ± 1.56 | 0.0008 | up-regulated |
Eotaxin | 0.07 ± 0.02 | 54.67 ± 8.47 | 0.0000 | up-regulated |
RANTES | 10.26 ± 1.62 | 234.04 ± 80.47 | 0.0015 | up-regulated |
IFN-γ | 29.91 ± 1.23 | 348.61 ± 62.18 | 0.0009 | up-regulated |
TNF-α | 1.09 ± 1.78 | 23.48 ± 3.46 | 0.0007 | up-regulated |
VEGF | 2021.13 ± 82.71 | 2929.27 ± 1180,89 | 0.0037 | up-regulated |