Skip to main content

Table 2 Hazard ratios for death (from any cause) among patients with NSCLC based on gene expression levels as determined via real-time quantitative RT-PCR and other parameters according to multivariate Cox regression analysisa

From: Hypoxia-induced Slug SUMOylation enhances lung cancer metastasis

Parameter Hazard ratio (95% CI) P
High Slug and Ubc9 expression 5.08 (1.99 to 12.92) 0.001
Other expression profiles 2.20 (0.82 to 5.91) 0.118
Sex 0.54 (0.24 to 1.20) 0.130
Histological type 0.66 (0.32 to 1.38) 0.268
Tumor size 1.04 (0.28 to 3.85) 0.949
Tumor stage 2.22 (1.48 to 3.33) 0.0001
  1. aA stepwise method was used to select the optimal multivariate Cox proportional hazard regression model. Slug and Ubc9 expression was designated as ‘high’ or ‘low’ using 0.6 as the cut-off value (low Slug and low Ubc9 as the references), and the results were adjusted according to sex (female as the reference vs. male), histological type (squamous cell carcinoma as the reference vs. adenocarcinoma), tumor size (≤ 3 cm as the reference vs. > 3 cm), and tumor stage. P values (two-sided) were calculated using a Pearson Chi-square test. Abbreviations: CI confidence interval