Table 2 Correlations between circDDX17 expression and clinicopathological parameters in CRC patients
Clinicopathological | Total (n = 60) | CircDDX17 expressiona | p value | |
|---|---|---|---|---|
parameters | Low (%) | High (%) | ||
Gender | ||||
 Male | 35 | 20(57.1%) | 15(42.9%) | 0.315 |
 Female | 25 | 11(44.0%) | 14(56.0%) |  |
Age(years) | ||||
 ≤ 65 | 26 | 12(46.2%) | 14(53.8%) | 0.455 |
 > 65 | 34 | 19(55.9%) | 15(44.1%) |  |
Tumor site | ||||
 Colon | 37 | 17(45.9%) | 20(54.1%) | 0.426 |
 Rectum | 23 | 13(56.5%) | 10(43.5%) |  |
Tumor size(cm) | ||||
 ≤ 5 | 36 | 17(47.2%) | 19(52.8%) | 0.598 |
 > 5 | 24 | 13(54.2%) | 11(45.8%) |  |
Lymphovascular invasion | ||||
 Absent | 22 | 7(31.8%) | 15 (68.2%) | 0.011* |
 Present | 38 | 25(65.8%) | 13(34.2%) |  |
Differentiation | ||||
 Well-moderate | 42 | 19(45.2%) | 23(54.8%) | 0.464 |
 Poor | 18 | 10(55.6%) | 8(44.4%) |  |
Depth of invasion | ||||
 T1-T2 | 21 | 7(33.3%) | 14(66.7%) | 0.007** |
 T3-T4 | 39 | 27(69.2%) | 12(30.8%) |  |
Lymph node metastasis | ||||
 N0 | 27 | 9(33.3%) | 18(66.7%) | 0.020* |
 N1-N2 | 33 | 21(63.6%) | 12(36.4%) |  |
Distant metastasis | ||||
 M0 | 43 | 15(34.9%) | 28(65.1%) | 0.012* |
 M1 | 17 | 12(70.6%) | 5(29.4%) |  |
TNM stage | ||||
 I-II | 26 | 10(38.5%) | 16 (61.5%) | 0.024* |
 III-IV | 34 | 23(67.6%) | 11(32.4%) |  |