Skip to main content
Fig. 7 | Journal of Experimental & Clinical Cancer Research

Fig. 7

From: RETRACTED ARTICLE: Endoplasmic reticulum stress triggers Xanthoangelol-induced protective autophagy via activation of JNK/c-Jun Axis in hepatocellular carcinoma

Fig. 7

p-JNK is required for the autophagy-induced by XAG in HCC cells. Cells were pre-treated with or without JNK inhibitor, SP600125 (20 μM), for 6 h, then were co-cultured with 20 μM of XAG for 48 h. a Expression levels of LC3B-II, p62/SQSTM1, Beclin-1, and Atg5 in HCC cells were analyzed by Western blotting, and GAPDH was severed as control group. **p<0.01. b Flow cytometry was performed to quantify the apoptotic cell ratio. **p<0.01. c The expression levels of Bax, Bcl-2, and cleaved caspase-3 in HCC cells were analyzed by Western blotting. GAPDH was served as control group as well. **p<0.01

Back to article page