Fig. 12

Up-regulation of miR-506 or silencing LHX2 inhibited tumor growth. a the positive expression rate of Ki67 protein in xenograft tumor tissues as measured by Immunohistochemistry; b the positive expression rate of Caspase-3 protein in xenograft tumor tissues as assessed by Immunohistochemistry; c miR-506 expression in xenograft tumor tissues as determined by RT-qPCR; d the protein levels of LHX2, Wnt1, β-catenin, E-cadherin, Vimentin, and Twist in xenograft tumor tissues as measured by western blot analysis; miR-506, microRNA-506; LHX2, LIM Homeobox 2; EMT, epithelial mesenchymal transition; NC, negative control; RT-qPCR, reverse transcription-quantitative polymerase chain reaction