Fig. 5

PAGE4 promotes prostate cancer cell growth but reduce tumor malignancy in vivo. a Tumor formation of DU145 cells with or without PAGE4 overexpression. Mice were feed with DOX in drinking water and NAC was administered by intraperitoneal injection. b Tumor weight in different groups, n = 8 in each group, *P < 0.05. c Expression of PAGE4 in xenografted tumor tissues was measured with Q-PCR, *P < 0.05. d Expression of ACTA2 in xenografted tumor tissues was measured with Q-PCR, *P < 0.05. e Expression of FBLN1 in xenografted tumor tissues was measured with Q-PCR, *P < 0.05. f Expression of F2R in xenografted tumor tissues was measured with Q-PCR, *P < 0.05. Three tumors were randomly picked and subjected to Q-PCR assay