Fig. 7
MAPK pathway changed when exposed to H2O2 in PAGE4 overexpressed cell lines. a Expression of MAPK pathway associated proteins in PAGE4 overexpressing cell lines with or without H2O2 treatment. Integral optical density (IOD) of each band were measured by using Gel-Pro Analyzer. b Immunohistochemical staining of pERK1/2 and PAGE4 in human prostate cancer tissues, red arrows showing a likely collocation of two proteins. c Hypothesis on PAGE4 regulating MAPK pathway under oxidative stress in prostate cancer cells