Journal of Experimental & Clinical Cancer Research

Table 2 The relationship between the expression of circ-SETD3 and the clinical characteristics of HCC patients

From: CircSETD3 (Hsa_circ_0000567) acts as a sponge for microRNA-421 inhibiting hepatocellular carcinoma growth

Parameters	Patient number (total = 132)	cric-SETD3 expression(2^-△△t)
Parameters	Patient number (total = 132)	mean ± SD	P value
Gender
Male	120	0.37 ± 0.20	0.81
Female	12	0.42 ± 0.42	0.81
Age (years)
≥60	64	0.33 ± 0.32	0.13
< 60	68	0.49 ± 0.46	0.13
HBV-DNA
≥10^3 copies/mL	71	0.36 ± 0.33	0.34
< 10^3 copies/mL	61	0.47 ± 0.48	0.34
AFP
≥400 ng/ml	64	0.40 ± 0.48	0.83
< 400 ng/ml	68	0.42 ± 0.33	0.83
Child-Pugh Grade
A	125	0.42 ± 0.41	0.46
B	7	0.24 ± 0.23	0.46
Tumor number
Multi	28	0.31 ± 0.43	0.33
Single	104	0.44 ± 0.40	0.33
Tumor size
≥5 cm	85	0.31 ± 0.32	0.01^*
< 5 cm	47	0.59 ± 0.49	0.01^*
Tumor capsule
Complete	52	0.48 ± 0.35	0.32
Infiltrate	80	0.37 ± 0.44	0.32
GVI
Present	38	0.45 ± 0.55	0.64
Absent	94	0.40 ± 0.34	0.64
BCLC stage
A	28	0.58 ± 0.29	0.26
B	59	0.35 ± 0.33
C	45	0.39 ± 0.53
MVI
Present	68	0.38 ± 0.46	0.57
Absent	64	0.44 ± 0.34	0.57
Differetiation
High + moderate	82	0.50 ± 0.46	0.01^*
Moderate to low + low	50	0.26 ± 0.23	0.01^*
Ishak score
0–2	5	0.18 ± 0.07	0.21
3–4	54	0.32 ± 0.28
5–6	73	0.49 ± 0.47

HCC hepatocellular carcinoma, AFP alpha fetal protein, HBsAg hepatitis B surface antigen, BCLC Barcelona-Clinic Liver Cancer, GVI gross vascular invasion defined as the tumor embolus were observed in the first or second branches of the portal veins by preoperative radiological tests, such as CT or MRI, MVI microvascular invasion, circSETD3 circular RNA SETD3, SD standard deviation
*statistical significance

Back to article page

ISSN: 1756-9966

Contact us

Submission enquiries: Access here and click Contact Us
General enquiries: info@biomedcentral.com