|
Clinicopathological Features
|
Univariate Analysis
|
Multivariate Analysis
|
|---|
|
HRa
|
95%CIb
|
P value
|
HRa
|
95%CIb
|
P value
|
|---|
|
Sex
|
0.809
|
0.313–2.088
|
0.661
| | | |
|
Age (years)
|
1.159
|
0.602–2.232
|
0.659
| | | |
|
ALT
|
1.770
|
0.684–4.577
|
0.239
| | | |
|
Tumor number
|
1.153
|
0.542–2.455
|
0.712
| | | |
|
Tumor capsule
|
0.617
|
0.319–1.194
|
0.151
| | | |
|
Serum AFP (ng/ml)
|
2.806
|
1.379–5.706
|
0.004
|
1.502
|
0.642–3.516
|
0.348
|
|
Tumor size (cm)
*
|
3.333
|
1.387–8.014
|
0.007
|
2.955
|
1.376–6.346
|
0.005
|
|
BCLC stage
|
2.561
|
1.326–4.947
|
0.005
|
0.439
|
0.156–1.231
|
0.118
|
|
TNM stage
|
2.613
|
1.351–5.055
|
0.004
|
0.400
|
0.139–1.149
|
0.089
|
|
Differentiation
|
0.507
|
0.262–0.981
|
0.044
|
0.766
|
0.339–1.731
|
0.521
|
|
Vascular invasion
|
4.154
|
2.049–8.421
|
0.000
|
0.885
|
0.351–2.234
|
0.796
|
|
FBXO22 overexpression
|
2.275
|
1.036–4.996
|
0.041
|
2.357
|
1.077–5.157
|
0.032
|
- a, hazard ratio; b, confidence interval
