Fig. 1

TRIM14 is increased in GBM tissues and cell lines. a Comparison of TRIM14 levels between normal brain tissues (NBT) and different grade glioblastoma specimens using qRT-PCR analysis. *p < 0.05; **p < 0.01; ***p < 0.001. b Western blot analysis of TRIM14 protein expression in different grade glioblastoma tissue and normal brain tissue. c Western blotting analysis of TRIM14 protein in 6 GBM samples and matched normal tissues. (N = normal tissues,T = GBM) (d) qPCR analysis of TRIM14 expression in 6 glioma cell lines as well as NHA controls. 6 cell lines show significantly increased TRIM14 protein levels. *p < 0.05; ***p < 0.001, n = 3 experiments. e The expression of TRIM14 is tested in normal brain tissues and glioma tissues (I-IV grade) from Jiangsu Province Hospital by Immunohistochemistry