|
Clinicopathological characteristics
|
Number of patients
|
Expression of circRNA_0000190 in tissuesa
|
P- value
|
|---|
|
Gender
|
|
Male
|
21
|
0.74 ± 0.08
|
0.192
|
|
Female
|
26
|
0.58 ± 0.08
|
|
Age (year)
|
|
< 42
|
24
|
0.64 ± 0.08
|
0.692
|
|
≥ 42
|
23
|
0.68 ± 0.09
|
|
M protein
|
|
IgG
|
14
|
0.66 ± 0.08
|
0.878
|
|
IgA
|
13
|
0.61 ± 0.11
|
|
Light chain
|
20
|
0.68 ± 0.10
|
|
ISS stage
|
|
I
|
8
|
1.10 ± 0.17
|
< 0.0001
|
|
II
|
16
|
0.78 ± 0.08
|
|
III
|
23
|
0.42 ± 0.04
|
|
Durie-Salmon stage
|
|
I
|
7
|
1.37 ± 0.09
|
< 0.0001
|
|
II
|
10
|
0.85 ± 0.07
|
|
III
|
30
|
0.43 ± 0.03
|
|
Hypercalcemia
|
|
With
|
15
|
0.75 ± 0.11
|
0.297
|
|
Without
|
32
|
0.62 ± 0.07
|
|
Renal insufficiency
|
|
With
|
16
|
0.71 ± 0.12
|
0.496
|
|
Without
|
31
|
0.63 ± 0.06
|
|
Anemia
|
|
With
|
38
|
0.63 ± 0.06
|
0.261
|
|
Without
|
9
|
0.79 ± 0.13
|
|
Bone disease
|
|
With
|
29
|
0.66 ± 0.08
|
0.81
|
|
Without
|
18
|
0.66 ± 0.08
|
|
Cytogenetic abnormality
|
|
With
|
12
|
0.73 ± 0.14
|
0.468
|
|
Without
|
36
|
0.63 ± 0.06
|
- a The relative expression of circRNA_0000190 was calculated using 2−∆∆Cq method and was shown as mean ± SE
