Skip to main content

Table 1 Difference in the circRNA_0000190 expression in multiple myeloma patients grouped by clinicopathological characteristics

From: CircRNA circ_0000190 inhibits the progression of multiple myeloma through modulating miR-767-5p/MAPK4 pathway

Clinicopathological characteristics Number of patients Expression of circRNA_0000190 in tissuesa P- value
Gender
 Male 21 0.74 ± 0.08 0.192
 Female 26 0.58 ± 0.08
Age (year)
  < 42 24 0.64 ± 0.08 0.692
  ≥ 42 23 0.68 ± 0.09
M protein
 IgG 14 0.66 ± 0.08 0.878
 IgA 13 0.61 ± 0.11
 Light chain 20 0.68 ± 0.10
ISS stage
 I 8 1.10 ± 0.17 < 0.0001
 II 16 0.78 ± 0.08
 III 23 0.42 ± 0.04
Durie-Salmon stage
 I 7 1.37 ± 0.09 < 0.0001
 II 10 0.85 ± 0.07
 III 30 0.43 ± 0.03
Hypercalcemia
 With 15 0.75 ± 0.11 0.297
 Without 32 0.62 ± 0.07
Renal insufficiency
 With 16 0.71 ± 0.12 0.496
 Without 31 0.63 ± 0.06
Anemia
 With 38 0.63 ± 0.06 0.261
 Without 9 0.79 ± 0.13
Bone disease
 With 29 0.66 ± 0.08 0.81
 Without 18 0.66 ± 0.08
Cytogenetic abnormality
 With 12 0.73 ± 0.14 0.468
 Without 36 0.63 ± 0.06
  1. a The relative expression of circRNA_0000190 was calculated using 2−∆∆Cq method and was shown as mean ± SE