Fig. 7

ALNPs exerted an antitumor effect in NPC cells. (a) ALNPs decreased the NPC cell colony formation ability. (b) ALNPs decreased the NPC cell migration ability. (c) ALNPs increased E-cadherin expression but decreased N-cadherin and vimentin expression. (d) ALNPs decreased the ALDH1+ labeling cell rate. (e) ALNPs decreased the PKH26+ labeling cell rate. (f) ALNPs decreased the SP rate. (g) ALNPs decreased the tumor sphere size. (h) ALNPs decreased the CSC-related markers SOX2, Nanog and c-myc. (i) ALNPs increased the NPC cell sensitivity to 5-Fu, as determined by an MTT assay. (j) ALNPs increased the NPC cell sensitivity to radiation, as determined by an MTT assay. (k) ALNPs increased the NPC cell sensitivity to 5-Fu in vivo. (l) ALNPs increased the NPC cell sensitivity to radiation in vivo