Table 2 M2 vaccine expressing MC38 neoantigens (see Fig. 3)
From: Poly-specific neoantigen-targeted cancer vaccines delay patient derived tumor growth
| Â | Â | WT Peptide | Neoantigen | Â | Â | ||||
|---|---|---|---|---|---|---|---|---|---|
# | Symbol | Seq | H2-Db | H2-Kb | Seq | H2-Db | H2-Kb | DAI | Imm. Resp. |
11 | Tmem135 | FALMNRKAL | 12 | 1426 | FALMNLKAL | 12 | 681 | < 5 | + |
12 | Aatf | MAPIDHTAM | 297 | 5239 | MAPIDHTTM | 90 | 6675 | > 5 | – |
13 | Spire1 | SAIRSYQDV | 814 | 271 | SAIRSYQYV | 28 | 43 | > 5 | + |
14 | Zbtb40 | KSFHFYCRL | 7827 | 4 | KSFHFYCPL | 1318 | 4 | < 5 | – |
15 | Slc12a4 | LSAARYALL | 26,865 | 16 | LSASRYALL | 27,697 | 14 | < 5 | – |
16 | Nfe2l2 | ASYSQVAHI | 4627 | 66 | ASYSLVAHI | 1309 | 23 | < 5 | – |
17 | Herc6 | CGYEHTAVL | 7636 | 140 | CVYEHTAVL | 9017 | 91 | < 5 | – |
18 | Copb2 | MSYFLQGKL | 6858 | 72 | MSYFLQGTL | 2039 | 51 | < 5 | – |
19 | Reps1 | AQLPNDVVL | 89 | 9261 | AQLANDVVL | 16 | 8591 | > 5 | + |
20 | Adpgk | ASMTNRELM | 6 | 2267 | ASMTNMELM | 4 | 1288 | < 5 | + |