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Table 2 SMC1A mutations identified in both adenoma and carcinoma samples

From: Overexpression of the cohesin-core subunit SMC1A contributes to colorectal cancer development

Subject Gender Stage Exon Nucleotide change Amino acid change
1 M Carcinoma 6 c.C1042T p.Q348X
Adenoma    
Mucosa    
2 M Carcinoma 14 c.A2267C p.Q756P
14 c.A2269G p.S757G
20 c.G3094A p.E1032K
24 c.T3544C p.F1182 L
Adenoma 16 c.2479 T p.Q827X
Mucosa    
3 M Carcinoma 9 c.A1448G p.Q483R
Adenoma 1 c.T40C p.S14P
Mucosa    
4 M Carcinoma 18 c.A2803G p.M935 V
18 c.T2804C p.M935 T
16 c.A2498G p.D833G
Adenoma    
Mucosa    
5 F Carcinoma    
Adenoma 1 c.101delA p.N34MfsX16
Mucosa    
6 M Carcinoma 12 c.G1928A p.G643E
12 c.G1966A p.A656T
Adenoma 17 c.A2662G p.N888D
Mucosa    
7 M Carcinoma 10 c.C1604T p.T535I
Adenoma    
Mucosa    
8 M Carcinoma    
Adenoma 4 c.A620G p.D207G
Mucosa    
9 F Carcinoma 6 c.T896C p.I299T
6 c.A950G p.K317R
Adenoma 22 c.C3421T p.L1141F
Mucosa    
10 M Carcinoma    
Adenoma 16 c.A2545G p.I849V
Mucosa    
11 F Carcinoma    
Adenoma 20 c.G3106A p.D1036N
Mucosa    
12 M Carcinoma 6 c.A950G p.K317R
6 c.G1027A p.V343 M
Adenoma 12 c.T1957C p.S653P
Mucosa    
13 M Carcinoma 13 c.A2027G p.E676G
Adenoma    
Mucosa    
14 F Carcinoma    
Adenoma    
Mucosa    
15 M Carcinoma    
Adenoma    
Mucosa    
16 M Carcinoma    
Adenoma    
Mucosa