Table 2 SMC1A mutations identified in both adenoma and carcinoma samples
From: Overexpression of the cohesin-core subunit SMC1A contributes to colorectal cancer development
Subject | Gender | Stage | Exon | Nucleotide change | Amino acid change |
|---|---|---|---|---|---|
1 | M | Carcinoma | 6 | c.C1042T | p.Q348X |
Adenoma | |||||
Mucosa | |||||
2 | M | Carcinoma | 14 | c.A2267C | p.Q756P |
14 | c.A2269G | p.S757G | |||
20 | c.G3094A | p.E1032K | |||
24 | c.T3544C | p.F1182 L | |||
Adenoma | 16 | c.2479 T | p.Q827X | ||
Mucosa | |||||
3 | M | Carcinoma | 9 | c.A1448G | p.Q483R |
Adenoma | 1 | c.T40C | p.S14P | ||
Mucosa | |||||
4 | M | Carcinoma | 18 | c.A2803G | p.M935 V |
18 | c.T2804C | p.M935 T | |||
16 | c.A2498G | p.D833G | |||
Adenoma | |||||
Mucosa | |||||
5 | F | Carcinoma | |||
Adenoma | 1 | c.101delA | p.N34MfsX16 | ||
Mucosa | |||||
6 | M | Carcinoma | 12 | c.G1928A | p.G643E |
12 | c.G1966A | p.A656T | |||
Adenoma | 17 | c.A2662G | p.N888D | ||
Mucosa | |||||
7 | M | Carcinoma | 10 | c.C1604T | p.T535I |
Adenoma | |||||
Mucosa | |||||
8 | M | Carcinoma | |||
Adenoma | 4 | c.A620G | p.D207G | ||
Mucosa | |||||
9 | F | Carcinoma | 6 | c.T896C | p.I299T |
6 | c.A950G | p.K317R | |||
Adenoma | 22 | c.C3421T | p.L1141F | ||
Mucosa | |||||
10 | M | Carcinoma | |||
Adenoma | 16 | c.A2545G | p.I849V | ||
Mucosa | |||||
11 | F | Carcinoma | |||
Adenoma | 20 | c.G3106A | p.D1036N | ||
Mucosa | |||||
12 | M | Carcinoma | 6 | c.A950G | p.K317R |
6 | c.G1027A | p.V343 M | |||
Adenoma | 12 | c.T1957C | p.S653P | ||
Mucosa | |||||
13 | M | Carcinoma | 13 | c.A2027G | p.E676G |
Adenoma | |||||
Mucosa | |||||
14 | F | Carcinoma | |||
Adenoma | |||||
Mucosa | |||||
15 | M | Carcinoma | |||
Adenoma | |||||
Mucosa | |||||
16 | M | Carcinoma | |||
Adenoma | |||||
Mucosa |