Table 1 Relationship between miR-3188 level and clinicopathologic features (N = 115)
From: Loss of exosomal miR-3188 in cancer-associated fibroblasts contributes to HNC progression
Characteristics | No. of Patients | miR-3188 ΔCta Mean ± SD | P value | |
|---|---|---|---|---|
No. | % | |||
Age (years) | ||||
 ≥ 60 | 53 | 46.1 | 7.894 ± 2.510 | 0.1616 |
 <  60 | 62 | 53.9 | 8.441 ± 1.848 | |
Gender | ||||
 Male | 82 | 71.3 | 8.352 ± 2.233 | 0.1503 |
 Female | 33 | 28.7 | 7.784 ± 2.030 | |
Smoking history | ||||
 Nonsmoker | 76 | 66.1 | 8.142 ± 2.378 | 0.8366 |
 Smoker | 39 | 33.9 | 8.280 ± 1.777 | |
Alcohol history | ||||
 Nondrinker | 82 | 71.3 | 8.156 ± 2.279 | 0.6264 |
 Drinker | 33 | 28.7 | 8.271 ± 1.964 | |
Tumor size (cm) | ||||
 ≤ 4 | 89 | 77.4 | 8.602 ± 1.796 | 0.0045 |
 >  4 | 26 | 22.6 | 6.776 ± 2.783 | |
Lymph node metastasis | ||||
 Non-metastasis | 63 | 54.8 | 8.062 ± 2.100 | 0.7506 |
 Metastasis | 52 | 45.2 | 8.343 ± 2.296 | |
TNM stage | ||||
 I | 69 | 60 | 8.668 ± 1.632 | 0.0160 |
 II | 41 | 35.7 | 8.182 ± 1.605 | |
 III | 5 | 4.3 | 7.347 ± 2.408 | |
Pathological Differentiation | ||||
 Well | 78 | 67.8 | 7.955 ± 2.301 | 0.2020 |
 Moderately/poorly | 37 | 32.2 | 8.683 ± 1.852 | |
Disease Site | ||||
 Tongue | 42 | 36.5 | 8.034 ± 2.020 | 0.9280 |
 Gingival | 36 | 31.3 | 8.196 ± 2.110 | |
 Cheek | 18 | 15.7 | 7.831 ± 2.442 | |
 Floor of Mouth | 12 | 10.4 | 8.702 ± 2.417 | |
 Oropharynx | 7 | 6.1 | 9.124 ± 2.684 | |