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Table 2 Relationship between BCL2 level and clinicopathologic features (N = 115)

From: Loss of exosomal miR-3188 in cancer-associated fibroblasts contributes to HNC progression

Characteristics

No. of Patients

BCL2 ΔCta

Mean ± SD

P value

No.

%

Age (years)

 ≥ 60

53

46.1

5.475 Â± 3.733

0.5450

 <  60

62

53.9

4.974 Â± 3.584

Gender

 Male

82

71.3

5.108 Â± 3.992

0.7880

 Female

33

28.7

5.445 Â± 2.631

Smoking history

 Nonsmoker

76

66.1

5.313 Â± 3.353

0.8890

 Smoker

39

33.9

4.994 Â± 4.196

Alcohol history

 Nondrinker

82

71.3

5.404 Â± 3.420

0.6564

 Drinker

33

28.7

4.710 Â± 4.196

Tumor size (cm)

 ≤ 4

89

77.4

4.682 Â± 3.567

0.0168

 >  4

26

22.6

6.994 Â± 3.393

Lymph node metastasis

 Non-metastasis

63

54.8

5.096 Â± 3.713

0.7979

 Metastasis

52

45.2

5.337 Â± 3.594

TNM stage

 I

69

60.0

5.835 Â± 2.991

0.3083

 II

41

35.7

4.282 Â± 3.924

 III

5

4.3

5.972 Â± 3.650

Pathological Differentiation

 Well

78

67.8

4.834 Â± 3.916

0.1040

 Moderately/poorly

37

32.2

5.986 Â± 2.891

Disease Site

 Tongue

42

36.5

4.654 Â± 4.016

0.1607

 Gingival

36

31.3

6.024 Â± 3.281

 Cheek

18

15.7

5.948 Â± 4.205

 Floor of Mouth

12

10.4

4.743 Â± 2.077

 Oropharynx

7

6.1

3.180 Â± 2.684

  1. Abbreviations: SD Standard deviation, TNM stage Tumor-lymph node-metastasis stage
  2. a△Ct indicates the difference in the cycle number at which a sample’s fluorescent signal passes a given threshold above baseline (Ct) derived from a specific gene compared with that of β-actin in tumor tissues