Fig. 9
From: ALKBH5 inhibited autophagy of epithelial ovarian cancer through miR-7 and BCL-2
ALKBH5 regulated tumorigenesis in nude mice model. a, b Mean tumor volume and weight on day 21 after tumor cell injection. LVRU6P-01- or LVRU6P-NC-infected SKOV3 cells were implanted subcutaneously into the left armpit. A2780 cells infected with LV121-NC or LV121-ALKBH5 were implanted subcutaneously into the left armpit. c IHC of ALKBH5, Bcl-2, p-AKT, p-ERK1/2, PIK3R1, p-MAPK, and p-mTOR expression was analyzed on tumor xenografts. Representative images are shown (original magnification 200X). *indicated P < 0.05. Scale bar: 50 μm