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Fig. 7 | Journal of Experimental & Clinical Cancer Research

Fig. 7

From: Knockdown of HMGA2 regulates the level of autophagy via interactions between MSI2 and Beclin1 to inhibit NF1-associated malignant peripheral nerve sheath tumour growth

Fig. 7

LBH589 inhibits NF1 MPNST cell growth through HMGA2-MSI2 interactions. a Cell viability was assessed by CCK-8 assays. LBH589 inhibits cell proliferation activity, while overexpression of HMGA2 reverses cell proliferation activity. The data represent the mean ± SD of three independent experiments. *P < 0.05 by Student’s t-tests. b and c WB and qRT-PCR were performed to detect the indicated protein and mRNA expression levels in NF1 MPNST cells. Bars represent the SEM. **P < 0.05 by Student’s t-tests

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