Fig. 4

Conditioned medium of M2-like macrophages enhances the migration property of K1 cells. Wound healing assay was performed on K1 cells treated with conditioned medium (CM) from macrophages exposed to CM from BCPAP (BCPAP-Macro), K1 (K1-Macro), senescent (STh-Macro) and proliferating thyrocytes (PTh-Macro), or from control M2 macrophages. The graph shows the percentage of wound closure quantified at the indicated time points (a) and specifically 8 h post-wound (b). Error bars represent standard deviation of two independent experiments. Statistical significance was determined by unpaired t test. *p < 0.05