Fig. 3

Cell Viability Assay. Dose-response effects of SI113 (green), QC (blue) and QC plus a constant (k) SI113 concentration (red) on percent cell viability (left panels) and histograms showing cell viability at selected drug concentrations, as indicated, to highlight the effect of the association of the two drugs (right panels). The effects of QC and SI113 combination drugs were considered synergistic when the CI was < 0.8 (in red). SI113 k values were 8.5, 7.9, 4.5, 4 and 6.5 μM for ADF (a), U373MG (b), T98G (c), GBM3-Luc (d) and GBM-I cells (e), respectively