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Fig. 7 | Journal of Experimental & Clinical Cancer Research

Fig. 7

From: Molecular pattern of lncRNAs in hepatocellular carcinoma

Fig. 7

HCC-associated lncRNAs in protein complex modulation. Upper panel: lncBRM regulates assembly of BAF complex by sequestering BRM, which leads to BRG1-embedded BAF complex being directed by KLF4 and binding with YAP1 promoter to activate YAP1 transcription subsequently. Lower panel: decreased lncBRM induces release of BRM, which facilitates BRM/BRG1 switch in BAF complex and inhibits YAP1 transcription

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