Fig. 1
From: Aberrant activation of CYR61 enhancers in colorectal cancer development
CYR61 expression levels in primary colonic adenocarcinoma patient samples and colon cell lines. a Immunostaining for CYR61 in paraffin sections of para-carcinoma tissues (a, b and cancer tissues (c, d from patients with colon adenocarcinoma (magnification, × 100, × 400). b The mean density of CYR61 in IHC of colon para-carcinoma and cancer tissues from 42 cases; significance determined by the paired-samples t-test. c Correlation between the mean density of CYR61 in IHC and TNM levels, significance determined by Spearman’s rank correlation. d CYR61 mRNA expression levels in primary colon cancer tissues compared with normal controls by analysis of the Hong Colorectal microarray dataset. e CYR61 mRNA expression levels in primary colon cancer tissues compared with normal controls by analysis of the Skrzypczak Colorectal 2 microarray dataset. f Expression of CYR61 mRNA and g protein levels in human colon cell lines, significance determined by the independent samples t-test. Data are shown as mean ± S.D., n = 3. *P < 0.05, **P < 0.01, ***P < 0.001