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Table 2 Univariate analysis of prognostic parameters for survival in patients with GC
| Prognostic parameter | HR | 95% CI | P value |
|---|---|---|---|
| Expression of GPAA1 (High vs Low) | 0.735 | 0.530–1.019 | 0.045 |
| Age (≥65 vs. < 65) | 1.486 | 1.142–1.932 | 0.003 |
| Gender (Male vs. Female) | 0.871 | 0.662–1.147 | 0.326 |
| TNM Stage (III-IV vs. I-II) | 4.754 | 3.487–6.482 | 0.000 |
| Tumor Size (≥4 cm vs. < 4 cm) | 3.192 | 2.274–4.481 | 0.000 |
| Pathology Grade (I, I-II, II vs. II-III, III) | 1.288 | 0.961–1.725 | 0.090 |
| Expression of ERBB2 (High vs Low) | 1.137 | 0.855–1.511 | 0.003 |
| Lymphatic metastasis (Present vs. Absent) | 3.852 | 2.751–5.934 | 0.000 |
| Distant metastasis (Present vs. Absent) | 1.176 | 0.165–8.395 | 0.871 |
| Vascular invasion (Present vs. Absent) | 2.435 | 1.795–3.303 | 0.000 |
| Perineuronal invasion (Present vs. Absent) | 2.152 | 1.531–3.025 | 0.000 |
| Histology (Poor vs. well & moderate) | 0.833 | 0.638–1.807 | 0.179 |
