Fig. 4

(a) CCK8 assay was used to detect the IC50 value of TNBC cell lines; (b) The Nek2B and β-catenin mRNA expression were detected by Q-RT-PCR after chemotherapy-sensitive cells MDA-MB-231 were treated with different concentrations of paclitaxel; (c) Nek2B-siRNA were transfected into drug-resistant cell Hs578T to test drug resistance reversal rate of Nek2B and β-catenin to paclitaxel. *P<0.05; **P<0.01