Fig. 8
From: Inhibition of RNA polymerase III transcription by Triptolide attenuates colorectal tumorigenesis
Pol III products are upregulated in CRC. a, b, c, d The expression of 5S rRNA (a), pre-tRNALeu (b), pre-tRNATyr (c), and 7SL RNA (d) from CRC tissues or adjacent non-cancer tissues was measured by real-time qPCR. The expression level was calculated as fold change with ACTB as endogenous control and normalized to the mean of non-cancerous group values. Dots indicate individual values. (e) The working model for triptolide-inhibited Pol III transcription and cancer cell growth