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Fig. 6 | Journal of Experimental & Clinical Cancer Research

Fig. 6

From: Hypoxia-inducible gene 2 promotes the immune escape of hepatocellular carcinoma from nature killer cells through the interleukin-10-STAT3 signaling pathway

Fig. 6

HIG2-silenced HepG2 and SMMC-7721 cells modulate the activity of NK cells through the STAT3 signaling pathway. a Phosphorylation levels of STAT1, STAT3, STAT4, and STAT5 in NK cells treated with the conditioned media of SMMC-7721 cells in the siR-HIG2 or siR-NC group, as determined by flow cytometry. *P<0.05 compared with the siR-NC group. b Expression of phosphorylated STAT3 protein in NK cells treated with the conditioned media of HepG2 or SMMC-7721 cells in the siR-HIG2 or siR-NC group, as determined by Western blotting. *P < 0.05 compared with siR-NC of the same cell type

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