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Table 1 Correlative analysis of SIRT7 mRNA levels with clinicopathological features. High tumoral SIRT7 expression was considered > 2-fold up-regulation relative to the adjacent non-tumoral liver. Correlations between SIRT7 and individual clinicopathologic parameters were evaluated using a nonparametric Fisher’s Exact Test

From: SIRT7 regulates hepatocellular carcinoma response to therapy by altering the p53-dependent cell death pathway

Clinicopatholigic Parameters

Number of Specimens

SIRT7 expression (Tumor/Nontumoral)

P value

low

high

Sex

   

1.000

 Female

6

2

4

 

 Male

11

4

7

 

Age(mean ± SD)

 

62.2 ± 4.7

62.7 ± 8.1

0.9598

Tumor size

   

0.6000

 > 3 cm

11

3

8

 

 < 3 cm

6

3

3

 

Multiple Tumor

   

0.2801

 Yes

12

3

9

 

 No

5

3

2

 

Vascular Invasion

   

0.0498

 Yes

9

1

8

 

 No

8

5

3

 

TACE Treatment

   

0.2801

 Yes

12

3

9

 

 No

5

3

2

 

Recurrence

   

0.5147

 Yes

2

0

2

 

 No

15

6

9

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